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Flights from Des Moines to San Diego, United States
Des Moines to San Diego Last modified: May 8, 2025 15:18 -04:00
We've scanned 122,775,531 round trip itineraries and found the cheapest flights to San Diego. Major Airlines & American frequently offer the best deals to San Diego flights, or select your preferred carrier below to see the cheapest days to fly.
Where To Buy Cheap Flights from Des Moines to San Diego?
The best way to find a great deal on airfare is to search multiple sites. When you run a search on FareCompare, we search multiple sites and fare sources all at once so you don't have to - which is why we think FareCompare is the best place to find cheap tickets. Airlines can adjust prices for tickets from Des Moines to San Diego based on the day and time that you decide to book your flight. We have collected data from all airlines, and have found that Tuesdays, Wednesdays, and Saturdays are often the best days to book flights. If you'd like to learn more, read our article about the best time to buy airline tickets.
Compare Flight Prices from Des Moines to San Diego by Month
Low priced flights are most commonly available by purchasing between one and three months in advance. International or holiday flights may need to be purchased even further in advance. The chart below shows the cheapest flight prices by month for Des Moines to San Diego flights.
| Month | Origin | Destination | Carrier | Depart Date | Return Date | Stops | Price |
|---|---|---|---|---|---|---|---|
| May | Des Moines | San Diego | Major Airlines | 5/20/25 | 5/24/25 | 1 | $287 |
| June | Des Moines | San Diego | Major Airlines | 6/2/25 | 6/6/25 | 1 | $287 |
Cheap Last Minute Flights from Des Moines to San Diego
Looking for cheap last minute flights or a weekend getaway? We've got you covered with weekend flight deals from Des Moines to San Diego. The chart below shows the best last minute deals and cheap flights this weekend we could find.
Next 30 Days
| Sun | Mon | Tue | Wed | Thu | Fri | Sat |
| 27 | 28 | 29 | 30 | 1 | 2 | 3 |
| $766 | ||||||
| 4 | 5 | 6 | 7 | 8 | 9 | 10 |
| $766 | $677 | |||||
| 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| $677 | $397 | |||||
| 18 | 19 | 20 | 21 | 22 | 23 | 24 |
| $397 | $287 | |||||
| 25 | 26 | 27 | 28 | 29 | 30 | 31 |
| $287 | $287 | |||||
| 1 | 2 | 3 | 4 | 5 | 6 | 7 |
| $287 | ||||||
Connecting Flights vs Direct Flights from Des Moines to San Diego
Flights between some cities may be significantly cheaper if you choose a multi-stop airline ticket. Although these connecting flights sacrifice some convenience, on average, travelers save 20%-60% when they choose to fly multi-stop versus a direct flight.
The average price for connecting flights from Des Moines to San Diego is $287.
The average price for direct flights from Des Moines to San Diego is not available.
One Way Flights vs Round Trip Flights from Des Moines to San Diego
We have found that there is often no price difference between buying a round trip flight versus a one way flight. Increased flexibility is the main benefit when it comes to buying a one way flight from Des Moines to San Diego. However, booking a round trip flight can be a simpler process. You can compare round trip and one way flights by using our flight comparison.
The average price for one way flights from Des Moines to San Diego is $107.
The average price for round trip flights from Des Moines to San Diego is $287.
Airlines in Des Moines flying to San Diego Last modified: May 8, 2025 15:18 -04:00Number of routes searched: 2Number of itineraries searched: 2
Wondering which airlines fly out of Des Moines to San Diego? We've gathered the average price of Des Moines airlines with flights to San Diego. Different airlines offer different levels of comfort and service, so consider convenience when choosing your airline.
Below is the full flight schedule summary showing which days of the week individual carriers offer flights for the next 30 days.
Farecompare Research Tools
FareCompare's Flight Schedule Search Tool helps you find information about airline schedule filings, including flight numbers, depart times, and travel distance.
Cheap Domestic Flights to San Diego - SAN Last modified: May 8, 2025 15:18 -04:00
