Flights from Des Moines to San Diego, United States

Did you mean flights from San Diego to Des Moines?

Des Moines to San Diego Last modified: May 8, 2025 15:18 -04:00

We've scanned 122,775,531 round trip itineraries and found the cheapest flights to San Diego. Major Airlines & American frequently offer the best deals to San Diego flights, or select your preferred carrier below to see the cheapest days to fly.

Major Airlines
DSMSAN
Tue 5/20
1 stop
SANDSM
Sat 5/24
1 stop
$287
American
DSMSAN
Tue 7/1
2 stops
SANDSM
Sat 7/5
2 stops
$352
United
DSMSAN
Tue 5/20
1 stop
SANDSM
Sat 5/24
1 stop
$367
Alaska
DSMSAN
Thu 8/7
1 stop
SANDSM
Tue 8/12
1 stop
$467
Frontier
DSMSAN
Mon 8/11
1 stop
SANDSM
Fri 8/15
1 stop
$472
Multiple Airlines
DSMSAN
Tue 5/20
1 stop
SANDSM
Sun 5/25
1 stop
$853

How Much is a Flight from Des Moines to San Diego?

We have collected flight cost data from across the web for travel from Des Moines to San Diego, and have found the average flight price for this trip to be $287.

Where To Buy Cheap Flights from Des Moines to San Diego?

The best way to find a great deal on airfare is to search multiple sites. When you run a search on FareCompare, we search multiple sites and fare sources all at once so you don't have to - which is why we think FareCompare is the best place to find cheap tickets. Airlines can adjust prices for tickets from Des Moines to San Diego based on the day and time that you decide to book your flight. We have collected data from all airlines, and have found that Tuesdays, Wednesdays, and Saturdays are often the best days to book flights. If you'd like to learn more, read our article about the best time to buy airline tickets.

How far in advance should I book tickets from Des Moines to San Diego?

The chart below shows up-to-date information regarding how far in advance to book your flight from Des Moines to San Diego.

Cheapest Day To Fly from Des Moines to San Diego

We've examined 245,551,062 itinerary searches that we've seen for departures in the next 90 days and found that the cheapest day to fly from Des Moines to San Diego is Sunday. See the chart below to compare prices for other days of the week.

Monday Tuesday Wednesday Thursday Friday Saturday Sunday
$287$287$287$287$287 $287

Compare Flight Prices from Des Moines to San Diego by Month

Low priced flights are most commonly available by purchasing between one and three months in advance. International or holiday flights may need to be purchased even further in advance. The chart below shows the cheapest flight prices by month for Des Moines to San Diego flights.

Month Origin Destination Carrier Depart Date Return Date Stops Price
May Des Moines San Diego Major Airlines 5/20/25 5/24/25 1 $287
June Des Moines San Diego Major Airlines 6/2/25 6/6/25 1 $287

Cheap Last Minute Flights from Des Moines to San Diego

Looking for cheap last minute flights or a weekend getaway? We've got you covered with weekend flight deals from Des Moines to San Diego. The chart below shows the best last minute deals and cheap flights this weekend we could find.

Next 30 Days

SunMonTueWedThuFriSat
27 28 29 30 1 2 3
$766
4 5 6 7 8 9 10
$766 $677
11 12 13 14 15 16 17
$677 $397
18 19 20 21 22 23 24
$397 $287
25 26 27 28 29 30 31
$287 $287
1 2 3 4 5 6 7
$287

Connecting Flights vs Direct Flights from Des Moines to San Diego

Flights between some cities may be significantly cheaper if you choose a multi-stop airline ticket. Although these connecting flights sacrifice some convenience, on average, travelers save 20%-60% when they choose to fly multi-stop versus a direct flight.

The average price for connecting flights from Des Moines to San Diego is $287.

The average price for direct flights from Des Moines to San Diego is not available.

One Way Flights vs Round Trip Flights from Des Moines to San Diego

We have found that there is often no price difference between buying a round trip flight versus a one way flight. Increased flexibility is the main benefit when it comes to buying a one way flight from Des Moines to San Diego. However, booking a round trip flight can be a simpler process. You can compare round trip and one way flights by using our flight comparison.

The average price for one way flights from Des Moines to San Diego is $107.

The average price for round trip flights from Des Moines to San Diego is $287.

Des Moines to San Diego Flight Questions

Airlines in Des Moines flying to San Diego Last modified: May 8, 2025 15:18 -04:00Number of routes searched: 2Number of itineraries searched: 2

Wondering which airlines fly out of Des Moines to San Diego? We've gathered the average price of Des Moines airlines with flights to San Diego. Different airlines offer different levels of comfort and service, so consider convenience when choosing your airline.

Below is the full flight schedule summary showing which days of the week individual carriers offer flights for the next 30 days.

Des Moines to San Diego
Airline Connections Mon Tue Wed Thu Fri Sat Sun
< Major Airlines < DEN < < < < < <
< Major Airlines < LAS < < < < < <

Farecompare Research Tools

FareCompare's Flight Schedule Search Tool helps you find information about airline schedule filings, including flight numbers, depart times, and travel distance.

Cheap Domestic Flights from Des Moines - DSM Last modified: May 8, 2025 15:18 -04:00

Cheap Flights from Des Moines to San Diego